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14-3-3 Proteins regulate mutant LRRK2 kinase activity and neurite shortening
Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common known cause of inherited Parkinson's disease (PD), and LRRK2 is a risk factor for idiopathic PD. How LRRK2 function is regulated is not well understood. Recently, the highly conserved 14-3-3 proteins, which play a key role in...
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| 出版年: | Hum Mol Genet |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4690493/ https://ncbi.nlm.nih.gov/pubmed/26546614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv453 |
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