Cargando...

The cohesin complex regulates immunoglobulin class switch recombination

Immunoglobulin (Ig) class switch recombination (CSR) is initiated by the transcription-coupled recruitment of activation-induced cytidine deaminase (AID) to switch regions and by the subsequent generation of double-stranded DNA breaks (DSBs). These DNA breaks are ultimately resolved through the nonh...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Thomas-Claudepierre, Anne-Sophie, Schiavo, Ebe, Heyer, Vincent, Fournier, Marjorie, Page, Adeline, Robert, Isabelle, Reina-San-Martin, Bernardo
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832931/
https://ncbi.nlm.nih.gov/pubmed/24145512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130166
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!