A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination

DNA double strand breaks (DSBs) are mainly repaired via homologous recombination (HR) or nonhomologous end joining (NHEJ). These breaks pose severe threats to genome integrity but can also be necessary intermediates of normal cellular processes such as immunoglobulin class switch recombination (CSR)...

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Main Authors: Enervald, Elin, Du, Likun, Visnes, Torkild, Björkman, Andrea, Lindgren, Emma, Wincent, Josephine, Borck, Guntram, Colleaux, Laurence, Cormier-Daire, Valerie, van Gent, Dik C., Pie, Juan, Puisac, Beatriz, de Miranda, Noel FCC, Kracker, Sven, Hammarström, Lennart, de Villartay, Jean-Pierre, Durandy, Anne, Schoumans, Jacqueline, Ström, Lena, Pan-Hammarström, Qiang
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2013
Teme:
Brief Definitive Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832922/
https://ncbi.nlm.nih.gov/pubmed/24145515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130168
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