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Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage

NIPBL is required to load the cohesin complex on to DNA. While the canonical role of cohesin is to couple replicated sister chromatids together until the onset of mitosis, it also promotes tolerance to DNA damage. Here, we show that NIPBL is recruited to DNA damage throughout the cell cycle via inde...

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Dettagli Bibliografici
Pubblicato in:J Cell Sci
Autori principali: Bot, Christopher, Pfeiffer, Annika, Giordano, Fosco, Manjeera, Dharani E., Dantuma, Nico P., Ström, Lena
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358341/
https://ncbi.nlm.nih.gov/pubmed/28167679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.197236
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