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Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage
NIPBL is required to load the cohesin complex on to DNA. While the canonical role of cohesin is to couple replicated sister chromatids together until the onset of mitosis, it also promotes tolerance to DNA damage. Here, we show that NIPBL is recruited to DNA damage throughout the cell cycle via inde...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5358341/ https://ncbi.nlm.nih.gov/pubmed/28167679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.197236 |
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