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Ikaros controls isotype selection during immunoglobulin class switch recombination
Class switch recombination (CSR) allows the humoral immune response to exploit different effector pathways through specific secondary antibody isotypes. However, the molecular mechanisms and factors that control immunoglobulin (Ig) isotype choice for CSR are unclear. We report that deficiency for th...
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| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715033/ https://ncbi.nlm.nih.gov/pubmed/19414557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082311 |
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