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Ikaros controls isotype selection during immunoglobulin class switch recombination

Class switch recombination (CSR) allows the humoral immune response to exploit different effector pathways through specific secondary antibody isotypes. However, the molecular mechanisms and factors that control immunoglobulin (Ig) isotype choice for CSR are unclear. We report that deficiency for th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sellars, MacLean, Reina-San-Martin, Bernardo, Kastner, Philippe, Chan, Susan
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715033/
https://ncbi.nlm.nih.gov/pubmed/19414557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082311
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