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Ikaros controls isotype selection during immunoglobulin class switch recombination

Class switch recombination (CSR) allows the humoral immune response to exploit different effector pathways through specific secondary antibody isotypes. However, the molecular mechanisms and factors that control immunoglobulin (Ig) isotype choice for CSR are unclear. We report that deficiency for th...

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Detalhes bibliográficos
Main Authors: Sellars, MacLean, Reina-San-Martin, Bernardo, Kastner, Philippe, Chan, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715033/
https://ncbi.nlm.nih.gov/pubmed/19414557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082311
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