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Ikaros in B cell development and function

The zinc finger transcription factor, Ikaros, is a central regulator of hematopoiesis. It is required for the development of the earliest B cell progenitors and at later stages for VDJ recombination and B cell receptor expression. Mature B cells rely on Ikaros to set the activation threshold for var...

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Detalhes bibliográficos
Main Authors: Sellars, MacLean, Kastner, Philippe, Chan, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135860/
https://ncbi.nlm.nih.gov/pubmed/21765979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v2.i6.132
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