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Ikaros Represses the Transcriptional Response to Notch Signaling in T-Cell Development
Notch activity is essential for early T-cell differentiation, but aberrant activity induces T-cell transformation. Thus, Notch target genes must be efficiently silenced in cells where Notch activity is no longer required. How these genes are repressed remains poorly understood. We report here that t...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593445/ https://ncbi.nlm.nih.gov/pubmed/18852286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00715-08 |
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