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Ikaros cooperates with Notch activation and antagonizes TGFβ signaling to promote pDC development
Plasmacytoid and conventional dendritic cells (pDCs and cDCs) arise from monocyte and dendritic progenitors (MDPs) and common dendritic progenitors (CDPs) through gene expression changes that remain partially understood. Here we show that the Ikaros transcription factor is required for DC developmen...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6042690/ https://ncbi.nlm.nih.gov/pubmed/30001316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007485 |
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