Llwytho...
Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL
The Notch pathway is frequently activated in T-cell acute lymphoblastic leukemias (T-ALLs). Of the Notch receptors, Notch1 is a recurrent target of gain-of-function mutations and Notch3 is expressed in all T-ALLs, but it is currently unclear how these receptors contribute to T-cell transformation in...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Society of Hematology
2010
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100247/ https://ncbi.nlm.nih.gov/pubmed/20829372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-286658 |
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