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Ikaros Represses the Transcriptional Response to Notch Signaling in T-Cell Development

Notch activity is essential for early T-cell differentiation, but aberrant activity induces T-cell transformation. Thus, Notch target genes must be efficiently silenced in cells where Notch activity is no longer required. How these genes are repressed remains poorly understood. We report here that t...

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Detaylı Bibliyografya
Asıl Yazarlar: Kleinmann, Eva, Geimer Le Lay, Anne-Solen, Sellars, MacLean, Kastner, Philippe, Chan, Susan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593445/
https://ncbi.nlm.nih.gov/pubmed/18852286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00715-08
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