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Ikaros controls isotype selection during immunoglobulin class switch recombination

Class switch recombination (CSR) allows the humoral immune response to exploit different effector pathways through specific secondary antibody isotypes. However, the molecular mechanisms and factors that control immunoglobulin (Ig) isotype choice for CSR are unclear. We report that deficiency for th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sellars, MacLean, Reina-San-Martin, Bernardo, Kastner, Philippe, Chan, Susan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715033/
https://ncbi.nlm.nih.gov/pubmed/19414557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082311
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