The cohesin complex regulates immunoglobulin class switch recombination

Immunoglobulin (Ig) class switch recombination (CSR) is initiated by the transcription-coupled recruitment of activation-induced cytidine deaminase (AID) to switch regions and by the subsequent generation of double-stranded DNA breaks (DSBs). These DNA breaks are ultimately resolved through the nonh...

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Detalhes bibliográficos
Main Authors: Thomas-Claudepierre, Anne-Sophie, Schiavo, Ebe, Heyer, Vincent, Fournier, Marjorie, Page, Adeline, Robert, Isabelle, Reina-San-Martin, Bernardo
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832931/
https://ncbi.nlm.nih.gov/pubmed/24145512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130166
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