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Structural and biological studies on bacterial nitric oxide synthase inhibitors

Nitric oxide (NO) produced by bacterial NOS functions as a cytoprotective agent against oxidative stress in Staphylococcus aureus, Bacillus anthracis, and Bacillus subtilis. The screening of several NOS-selective inhibitors uncovered two inhibitors with potential antimicrobial properties. These two...

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Detalhes bibliográficos
Main Authors: Holden, Jeffrey K., Li, Huiying, Jing, Qing, Kang, Soosung, Richo, Jerry, Silverman, Richard B., Poulos, Thomas L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831449/
https://ncbi.nlm.nih.gov/pubmed/24145412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314080110
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