Heat Shock Proteins Regulate Activation-induced Proteasomal Degradation of the Mature Phosphorylated Form of Protein Kinase C

Although alterations in stimulus-induced degradation of PKC have been implicated in disease, mechanistic understanding of this process remains limited. Evidence supports the existence of both proteasomal and lysosomal mechanisms of PKC processing. An established pathway involves rate-limiting primin...

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Bibliografiska uppgifter
Huvudupphovsmän: Lum, Michelle A., Balaburski, Gregor M., Murphy, Maureen E., Black, Adrian R., Black, Jennifer D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2013
Ämnen:
Protein Synthesis and Degradation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779710/
https://ncbi.nlm.nih.gov/pubmed/23900841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.437095
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