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Heat Shock Proteins Regulate Activation-induced Proteasomal Degradation of the Mature Phosphorylated Form of Protein Kinase C

Although alterations in stimulus-induced degradation of PKC have been implicated in disease, mechanistic understanding of this process remains limited. Evidence supports the existence of both proteasomal and lysosomal mechanisms of PKC processing. An established pathway involves rate-limiting primin...

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Autors principals: Lum, Michelle A., Balaburski, Gregor M., Murphy, Maureen E., Black, Adrian R., Black, Jennifer D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779710/
https://ncbi.nlm.nih.gov/pubmed/23900841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.437095
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