Heat Shock Protein 70 Inhibits HIV-1 Vif-mediated Ubiquitination and Degradation of APOBEC3G

The cytidine deaminase APOBEC3G, which is incorporated into nascent virus particles, possesses potent antiviral activity and restricts Vif-deficient HIV-1 replication at the reverse transcription step through deamination-dependent and -independent effects. HIV-1 Vif counteracts the antiviral activit...

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Detalhes bibliográficos
Main Authors: Sugiyama, Ryuichi, Nishitsuji, Hironori, Furukawa, Ayako, Katahira, Masato, Habu, Yuichiro, Takeuchi, Hiroaki, Ryo, Akihide, Takaku, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Protein Synthesis and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060456/
https://ncbi.nlm.nih.gov/pubmed/21228271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.166108
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