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The Proteasome-associated Protein Ecm29 Inhibits Proteasomal ATPase Activity and in Vivo Protein Degradation by the Proteasome

Several proteasome-associated proteins regulate degradation by the 26 S proteasome using the ubiquitin chains that mark most substrates for degradation. The proteasome-associated protein Ecm29, however, has no ubiquitin-binding or modifying activity, and its direct effect on substrate degradation is...

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Bibliografiske detaljer
Main Authors: De La Mota-Peynado, Alina, Lee, Stella Yu-Chien, Pierce, Brianne Marie, Wani, Prashant, Singh, Chingakham Ranjit, Roelofs, Jeroen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795246/
https://ncbi.nlm.nih.gov/pubmed/23995839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.491662
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