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Starvation Induces Proteasome Autophagy with Different Pathways for Core and Regulatory Particles

The proteasome is responsible for the degradation of many cellular proteins. If and how this abundant and normally stable complex is degraded by cells is largely unknown. Here we show that in yeast, upon nitrogen starvation, proteasomes are targeted for vacuolar degradation through autophagy. Using...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Waite, Kenrick A., Mota-Peynado, Alina De-La, Vontz, Gabrielle, Roelofs, Jeroen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751371/
https://ncbi.nlm.nih.gov/pubmed/26670610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.699124
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