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Phosphorylation of the C-terminal tail of proteasome subunit α7 is required for binding of the proteasome quality control factor Ecm29

The proteasome degrades many short-lived proteins that are labeled with an ubiquitin chain. The identification of phosphorylation sites on the proteasome subunits suggests that degradation of these substrates can also be regulated at the proteasome. In yeast and humans, the unstructured C-terminal r...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wani, Prashant S., Suppahia, Anjana, Capalla, Xavier, Ondracek, Alex, Roelofs, Jeroen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908598/
https://ncbi.nlm.nih.gov/pubmed/27302526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27873
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