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Phosphorylation of the C-terminal tail of proteasome subunit α7 is required for binding of the proteasome quality control factor Ecm29

The proteasome degrades many short-lived proteins that are labeled with an ubiquitin chain. The identification of phosphorylation sites on the proteasome subunits suggests that degradation of these substrates can also be regulated at the proteasome. In yeast and humans, the unstructured C-terminal r...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Wani, Prashant S., Suppahia, Anjana, Capalla, Xavier, Ondracek, Alex, Roelofs, Jeroen
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908598/
https://ncbi.nlm.nih.gov/pubmed/27302526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27873
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