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Sulforaphane Activates Heat Shock Response and Enhances Proteasome Activity through Up-regulation of Hsp27

It is conceivable that stimulating proteasome activity for rapid removal of misfolded and oxidized proteins is a promising strategy to prevent and alleviate aging-related diseases. Sulforaphane (SFN), an effective cancer preventive agent derived from cruciferous vegetables, has been shown to enhance...

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Detalles Bibliográficos
Main Authors: Gan, Nanqin, Wu, Yu-Chieh, Brunet, Mathilde, Garrido, Carmen, Chung, Fung-Lung, Dai, Chengkai, Mi, Lixin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975177/
https://ncbi.nlm.nih.gov/pubmed/20833711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.152686
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