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Evaluation of NHS Carbamates as a Potent and Selective Class of Endocannabinoid Hydrolase Inhibitors
[Image: see text] Monoacylglycerol lipase (MAGL) is a principal metabolic enzyme responsible for hydrolyzing the endogenous cannabinoid (endocannabinoid) 2-arachidonoylglycerol (2-AG). Selective inhibitors of MAGL offer valuable probes to further understand the enzyme’s function in biological system...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American
Chemical Society
2013
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3778430/ https://ncbi.nlm.nih.gov/pubmed/23731016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400116z |
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