Inhibition of DNA damage repair by artificial activation of PARP with siDNA

One of the major early steps of repair is the recruitment of repair proteins at the damage site, and this is coordinated by a cascade of modifications controlled by phosphatidylinositol 3-kinase-related kinases and/or poly (ADP-ribose) polymerase (PARP). We used short interfering DNA molecules mimic...

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Detalhes bibliográficos
Main Authors: Croset, Amelie, Cordelières, Fabrice P., Berthault, Nathalie, Buhler, Cyril, Sun, Jian-Sheng, Quanz, Maria, Dutreix, Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753643/
https://ncbi.nlm.nih.gov/pubmed/23761435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt522
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