Inhibition of DNA damage repair by artificial activation of PARP with siDNA

One of the major early steps of repair is the recruitment of repair proteins at the damage site, and this is coordinated by a cascade of modifications controlled by phosphatidylinositol 3-kinase-related kinases and/or poly (ADP-ribose) polymerase (PARP). We used short interfering DNA molecules mimic...

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Autors principals: Croset, Amelie, Cordelières, Fabrice P., Berthault, Nathalie, Buhler, Cyril, Sun, Jian-Sheng, Quanz, Maria, Dutreix, Marie
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Genome Integrity, Repair and Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753643/
https://ncbi.nlm.nih.gov/pubmed/23761435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt522
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