Inhibition of DNA damage repair by artificial activation of PARP with siDNA

One of the major early steps of repair is the recruitment of repair proteins at the damage site, and this is coordinated by a cascade of modifications controlled by phosphatidylinositol 3-kinase-related kinases and/or poly (ADP-ribose) polymerase (PARP). We used short interfering DNA molecules mimic...

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Bibliografski detalji
Glavni autori: Croset, Amelie, Cordelières, Fabrice P., Berthault, Nathalie, Buhler, Cyril, Sun, Jian-Sheng, Quanz, Maria, Dutreix, Marie
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Genome Integrity, Repair and Replication
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753643/
https://ncbi.nlm.nih.gov/pubmed/23761435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt522
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