Design and Synthesis of Potent “Sulfur-free” Transition State Analogue Inhibitors of 5′-Methylthioadenosine Nucleosidase and 5′-Methylthioadenosine Phosphorylase

Eitemau Tebyg

• Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimics
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  Cyhoeddwyd: (2012)
• Transition-State Analogues of Campylobacter jejuni 5′-Methylthioadenosine Nucleosidase
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  Cyhoeddwyd: (2018)
• Transition state analogues of 5′-methylthioadenosine nucleosidase disrupt quorum sensing
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  Cyhoeddwyd: (2009)
• Selective Inhibitors of Helicobacter pylori Methylthioadenosine Nucleosidase and Human Methylthioadenosine Phosphorylase
  gan: Harijan, Rajesh K., et al.
  Cyhoeddwyd: (2019)
• Transition State Analogue Inhibitors of 5′-Deoxyadenosine/5′-Methylthioadenosine Nucleosidase from Mycobacterium tuberculosis
  gan: Namanja-Magliano, Hilda A., et al.
  Cyhoeddwyd: (2017)