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Transcription-induced barriers to supercoil diffusion in the Salmonella typhimurium chromosome

Transcription and replication both influence and are influenced by superhelical changes in DNA. Explaining how supercoil movement is channeled in living chromosomes has been a major problem for 30 years. Transcription of membrane-associated proteins leads to localized hypersupercoiling of plasmid DN...

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Detalles Bibliográficos
Main Authors: Deng, Shuang, Stein, Richard A., Higgins, N. Patrick
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC373473/
https://ncbi.nlm.nih.gov/pubmed/14993611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307550101
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