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Crystal structure of reverse gyrase: insights into the positive supercoiling of DNA
Reverse gyrase is the only topoisomerase known to positively supercoil DNA. The protein appears to be unique to hyperthermophiles, where its activity is believed to protect the genome from denaturation. The 120 kDa enzyme is the only member of the type I topoisomerase family that requires ATP, which...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125824/ https://ncbi.nlm.nih.gov/pubmed/11823434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.3.418 |
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