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Transcription-induced barriers to supercoil diffusion in the Salmonella typhimurium chromosome

Transcription and replication both influence and are influenced by superhelical changes in DNA. Explaining how supercoil movement is channeled in living chromosomes has been a major problem for 30 years. Transcription of membrane-associated proteins leads to localized hypersupercoiling of plasmid DN...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Deng, Shuang, Stein, Richard A., Higgins, N. Patrick
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC373473/
https://ncbi.nlm.nih.gov/pubmed/14993611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307550101
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