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Transcription-induced barriers to supercoil diffusion in the Salmonella typhimurium chromosome

Transcription and replication both influence and are influenced by superhelical changes in DNA. Explaining how supercoil movement is channeled in living chromosomes has been a major problem for 30 years. Transcription of membrane-associated proteins leads to localized hypersupercoiling of plasmid DN...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Deng, Shuang, Stein, Richard A., Higgins, N. Patrick
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373473/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14993611/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307550101
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