Transcription-induced barriers to supercoil diffusion in the Salmonella typhimurium chromosome

Transcription and replication both influence and are influenced by superhelical changes in DNA. Explaining how supercoil movement is channeled in living chromosomes has been a major problem for 30 years. Transcription of membrane-associated proteins leads to localized hypersupercoiling of plasmid DN...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Deng, Shuang, Stein, Richard A., Higgins, N. Patrick
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 2004
Предметы:	Biological Sciences
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373473/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14993611/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307550101
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