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Transcription-induced barriers to supercoil diffusion in the Salmonella typhimurium chromosome

Transcription and replication both influence and are influenced by superhelical changes in DNA. Explaining how supercoil movement is channeled in living chromosomes has been a major problem for 30 years. Transcription of membrane-associated proteins leads to localized hypersupercoiling of plasmid DN...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Deng, Shuang, Stein, Richard A., Higgins, N. Patrick
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373473/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14993611/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307550101
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