Identification of Benzimidazole Diamides as Selective Inhibitors of the Nucleotide-Binding Oligomerization Domain 2 (NOD2) Signaling Pathway

NOD2 is an intracellular pattern recognition receptor that assembles with receptor-interacting protein (RIP)-2 kinase in response to the presence of bacterial muramyl dipeptide (MDP) in the host cell cytoplasm, thereby inducing signals leading to the production of pro-inflammatory cytokines. The dys...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Rickard, David J., Sehon, Clark A., Kasparcova, Viera, Kallal, Lorena A., Zeng, Xin, Montoute, Monica N., Chordia, Tushar, Poore, Derek D., Li, Hu, Wu, Zining, Eidam, Patrick M., Haile, Pamela A., Yu, Jong, Emery, John G., Marquis, Robert W., Gough, Peter J., Bertin, John
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731320/
https://ncbi.nlm.nih.gov/pubmed/23936340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069619
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares