Identification of Selective Small Molecule Inhibitors of the Nucleotide-Binding Oligomerization Domain 1 (NOD1) Signaling Pathway

NOD1 is an intracellular pattern recognition receptor that recognizes diaminopimelic acid (DAP), a peptidoglycan component in gram negative bacteria. Upon ligand binding, NOD1 assembles with receptor-interacting protein (RIP)-2 kinase and initiates a signaling cascade leading to the production of pr...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Rickard, David J., Sehon, Clark A., Kasparcova, Viera, Kallal, Lorena A., Haile, Pamela A., Zeng, Xin, Montoute, Monica N., Poore, Derek D., Li, Hu, Wu, Zining, Eidam, Patrick M., Emery, John G., Marquis, Robert W., Gough, Peter J., Bertin, John
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013053/
https://ncbi.nlm.nih.gov/pubmed/24806487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096737
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares