SAHA overcomes FLIP-mediated inhibition of SMAC mimetic-induced apoptosis in mesothelioma

Malignant pleural mesothelioma (MPM) is a highly pro-inflammatory malignancy that is rapidly fatal and increasing in incidence. Cytokine signaling within the pro-inflammatory tumor microenvironment makes a critical contribution to the development of MPM and its resistance to conventional chemotherap...

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Autors principals: Crawford, N, Stasik, I, Holohan, C, Majkut, J, McGrath, M, Johnston, P G, Chessari, G, Ward, G A, Waugh, D J, Fennell, D A, Longley, D B
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730428/
https://ncbi.nlm.nih.gov/pubmed/23868066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.258
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