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Peripheral Reduction of FGFR4 with Antisense Oligonucleotides Increases Metabolic Rate and Lowers Adiposity in Diet-Induced Obese Mice

Obesity is a primary risk factor for multiple metabolic disorders. Many drugs for the treatment of obesity, which mainly act through CNS as appetite suppressants, have failed during development or been removed from the market due to unacceptable adverse effects. Thus, there are very few efficacious...

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書誌詳細
主要な著者: Yu, Xing Xian, Watts, Lynnetta M., Manchem, Vara Prasad, Chakravarty, Kaushik, Monia, Brett P., McCaleb, Michael L., Bhanot, Sanjay
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726752/
https://ncbi.nlm.nih.gov/pubmed/23922646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066923
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