Muscle-specific Pikfyve gene disruption causes glucose intolerance, insulin resistance, adiposity, and hyperinsulinemia but not muscle fiber-type switching

The evolutionarily conserved kinase PIKfyve that synthesizes PtdIns5P and PtdIns(3,5)P(2) has been implicated in insulin-regulated GLUT4 translocation/glucose entry in 3T3-L1 adipocytes. To decipher PIKfyve's role in muscle and systemic glucose metabolism, here we have developed a novel mouse m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ikonomov, Ognian C., Sbrissa, Diego, Delvecchio, Khortnal, Feng, Han-Zhong, Cartee, Gregory D., Jin, Jian-Ping, Shisheva, Assia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2013
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725567/
https://ncbi.nlm.nih.gov/pubmed/23673157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00030.2013
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak