Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability

Secondary alkylcarbamic acid biphenyl-3-yl esters are a class of Fatty Acid Amide Hydrolase (FAAH) inhibitors, which include the reference compounds URB597 and URB694. Given the intrinsic reactivity of the carbamate group, the in vivo potency of these molecules in rats is strongly affected by their...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Vacondio, Federica, Silva, Claudia, Lodola, Alessio, Carmi, Caterina, Rivara, Silvia, Duranti, Andrea, Tontini, Andrea, Sanchini, Silvano, Clapper, Jason R., Piomelli, Daniele, Tarzia, Giorgio, Mor, Marco
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714604/
https://ncbi.nlm.nih.gov/pubmed/21820769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.07.021
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares