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Evolution of the cancer genome

Human tumors result from an evolutionary process operating on somatic cells within tissues, whereby natural selection operates on the phenotypic variability generated by the accumulation of genetic, genomic and epigenetic alterations. This somatic evolution leads to adaptations such as increased pro...

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Détails bibliographiques
Auteurs principaux: Podlaha, Ondrej, Riester, Markus, De, Subhajyoti, Michor, Franziska
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711268/
https://ncbi.nlm.nih.gov/pubmed/22342180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2012.01.003
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