Načítá se...
DNA replication timing and higher-order nuclear organization determine single nucleotide substitution patterns in cancer genomes
Single nucleotide substitutions (SNS) are a defining characteristic of cancer genomes. Many SNS in cancer genomes arise due to errors in DNA replication, which is spatio-temporally stratified. Here we propose that DNA replication patterns help shape the mutational landscapes of normal and cancer gen...
Uloženo v:
| Hlavní autoři: | , , |
|---|---|
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633418/ https://ncbi.nlm.nih.gov/pubmed/23422670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2502 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|