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DNA secondary structures and epigenetic determinants of cancer genome evolution
An unstable genome is a hallmark of many cancers. It is unclear, however, whether some mutagenic features driving somatic alterations in cancer are encoded in the genome sequence and whether they can operate in a tissue-specific manner. We performed a genome-wide analysis of 663,446 DNA breakpoints...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3963273/ https://ncbi.nlm.nih.gov/pubmed/21725294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2089 |
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