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DNA secondary structures and epigenetic determinants of cancer genome evolution

An unstable genome is a hallmark of many cancers. It is unclear, however, whether some mutagenic features driving somatic alterations in cancer are encoded in the genome sequence and whether they can operate in a tissue-specific manner. We performed a genome-wide analysis of 663,446 DNA breakpoints...

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Bibliografiska uppgifter
Huvudupphovsmän: De, Subhajyoti, Michor, Franziska
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963273/
https://ncbi.nlm.nih.gov/pubmed/21725294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2089
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