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Evolution of the cancer genome

Human tumors result from an evolutionary process operating on somatic cells within tissues, whereby natural selection operates on the phenotypic variability generated by the accumulation of genetic, genomic and epigenetic alterations. This somatic evolution leads to adaptations such as increased pro...

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Detalhes bibliográficos
Main Authors: Podlaha, Ondrej, Riester, Markus, De, Subhajyoti, Michor, Franziska
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711268/
https://ncbi.nlm.nih.gov/pubmed/22342180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2012.01.003
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