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DNA replication timing and long-range DNA interactions predict mutational landscapes of cancer genomes
Somatic copy-number alterations (SCNA) are a hallmark of many cancer types, but the mechanistic basis underlying their genome-wide patterns remains incompletely understood. Here we integrate data on DNA replication timing, long-range interactions between genomic material, and 331,724 SCNAs from 2,79...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3923360/ https://ncbi.nlm.nih.gov/pubmed/22101487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2030 |
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