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The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes
Methylated cytosines (5mCs) are frequently mutated in the genome. However, no studies have yet comprehensively analysed mutation–methylation associations across cancer types. Here we analyse 916 cancer genomes, together with tissue type-specific methylation and replication timing data. We describe a...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5737810/ https://ncbi.nlm.nih.gov/pubmed/28531315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx463 |
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