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Histone Modifications Are Associated with Transcript Isoform Diversity in Normal and Cancer Cells

Mechanisms that generate transcript diversity are of fundamental importance in eukaryotes. Although a large fraction of human protein-coding genes and lincRNAs produce more than one mRNA isoform each, the regulation of this phenomenon is still incompletely understood. Much progress has been made in...

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Detalhes bibliográficos
Main Authors: Podlaha, Ondrej, De, Subhajyoti, Gonen, Mithat, Michor, Franziska
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046914/
https://ncbi.nlm.nih.gov/pubmed/24901363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003611
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