טוען...
Continuous DOPA synthesis from a single AAV: dosing and efficacy in models of Parkinson's disease
We used a single adeno-associated viral (AAV) vector co-expressing tyrosine hydroxylase (TH) and GTP cyclohydrolase 1 (GCH1) to investigate the relationship between vector dose, and the magnitude and rate of recovery in hemi-parkinsonian rats. Intrastriatal injections of >1E10 genomic copies (gc)...
שמור ב:
| Main Authors: | , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3703607/ https://ncbi.nlm.nih.gov/pubmed/23831692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02157 |
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