Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells

The thymus provides multiple microenvironments that are essential for the development and repertoire selection of T lymphocytes. The thymic cortex induces the generation and positive selection of T lymphocytes, whereas the thymic medulla establishes self-tolerance among the positively selected T lym...

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Main Authors: Ohigashi, Izumi, Zuklys, Saulius, Sakata, Mie, Mayer, Carlos E., Zhanybekova, Saule, Murata, Shigeo, Tanaka, Keiji, Holländer, Georg A., Takahama, Yousuke
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2013
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683726/
https://ncbi.nlm.nih.gov/pubmed/23720310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301799110
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