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Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells
The thymus provides multiple microenvironments that are essential for the development and repertoire selection of T lymphocytes. The thymic cortex induces the generation and positive selection of T lymphocytes, whereas the thymic medulla establishes self-tolerance among the positively selected T lym...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3683726/ https://ncbi.nlm.nih.gov/pubmed/23720310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301799110 |
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