Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells

The thymus supports multiple αβ T cell lineages that are functionally distinct, but mechanisms that control this multifaceted development are poorly understood. Here we examine medullary thymic epithelial cell (mTEC) heterogeneity and its influence on CD1d-restricted iNKT cells. We find three distin...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Lucas, Beth, White, Andrea J., Cosway, Emilie J., Parnell, Sonia M., James, Kieran D., Jones, Nick D., Ohigashi, Izumi, Takahama, Yousuke, Jenkinson, William E., Anderson, Graham
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198500/
https://ncbi.nlm.nih.gov/pubmed/32366944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16041-x
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