Serial progression of cortical and medullary thymic epithelial microenvironments

Thymic epithelial cells (TECs) provide key instructive signals for T-cell differentiation. Thymic cortical (cTECs) and medullary (mTECs) epithelial cells constitute two functionally distinct microenvironments for T-cell development, which derive from a common bipotent TEC progenitor. While seminal s...

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Udgivet i:Eur J Immunol
Main Authors: Alves, Nuno L, Takahama, Yousuke, Ohigashi, Izumi, Ribeiro, Ana R, Baik, Song, Anderson, Graham, Jenkinson, William E
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2014
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253091/
https://ncbi.nlm.nih.gov/pubmed/24214487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344110
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